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TBR-652 blocks both CCR5 and CCR2, inhibiting HIV replication and reducing inflammation

Date: 20-07-2010

TBR-652, a dual antagonist or blocker of both the CCR5 and CCR2 cell surface receptors, shows potent activity against HIV and also dampens inflammation, participants heard at the Eighteenth International AIDS Conference this week in Vienna. HIV can use two different surface co-receptors - CCR5 and CXCR4 - along with the CD4 receptor to enter

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